IV Ketamine Therapy in Chicago

A new perspective on mental wellness.

Medically supervised care, when your current approach isn’t enough.

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OptionsIV ketamine or Spravato®
Care teamMedical and psychiatric
SettingPrivate, with monitoring
Your planAfter a full evaluation
MembershipsIV ketamine in Balance and Longevity

The science behind the shift

A different pathway, a new possibility.

IV ketamine works differently from traditional antidepressants.

It acts on the brain’s glutamate system and NMDA receptors, pathways linked to neural communication and neuroplasticity, the brain’s ability to form new connections. It is studied for depression and treatment-resistant depression, and may be an option when conventional approaches have not worked well enough.

Our approach

At Modern Wellness, IV ketamine is never a stand-alone answer. It is one branch of a whole-person plan that also looks at your roots:

  • Sleep
  • Nutrition
  • Inflammation
  • Stress
  • Your support

Our medical team reviews your health history, goals and needs before recommending IV ketamine, in a private, supportive setting on Michigan Avenue.

When your current approach isn’t enough

Who IV ketamine may help.

Tap each icon to explore.

Depression

When low mood, motivation and energy persist, IV ketamine may be considered as part of your plan.

MoodMotivationEnergy

Treatment-resistant depression

For people who have tried several antidepressants without enough relief, after a careful provider review.

Prior treatmentsProvider review

Anxiety

May be considered for anxiety, as one part of a broader mental wellness plan.

WorryOverwhelmBalance

PTSD

A supervised option that may support people living with trauma, alongside therapy and other care.

TraumaSupervisedSupportive

Mood booster

For people who want to lift their mood and feel more like themselves, as part of a whole-person plan and after a provider evaluation.

MoodEnergyWell-being

Two options, one standard of care

IV ketamine and Spravato®, in plain words.

IV infusion

IV ketamine

A slow infusion, with the dose set and adjusted by our medical team.

At Modern Wellness

In a private, calm room, monitored by a nurse practitioner for up to two hours.

Nasal spray

Spravato®

Esketamine, a form of ketamine, given as a nasal spray. It is FDA-approved for certain adults with depression.

At Modern Wellness

Taken in our clinic under supervision, with at least two hours of monitoring after each dose.

Your provider helps you decide which option, if any, is right for you.

The holistic difference

Care that goes beyond a single treatment.

IV ketamine is never a stand-alone answer. It is one component of a broader mental wellness strategy, and your plan is adjusted based on how you respond and on your provider’s recommendations.

The goal is not to promise an outcome, but to open a new door with care.

A new pathway

The science

IV ketamine acts on the glutamate system and NMDA receptors, pathways linked to neuroplasticity, the brain’s ability to form new connections.

GlutamateNMDA receptorsNeuroplasticity
Medically supervised

The infusion

IV ketamine or Spravato® in a calm, private clinical setting, with medical monitoring from start to finish.

IV infusionMonitoringPrivate setting
Beyond one treatment

Your broader plan

IV ketamine is one part of your care, alongside therapy, coaching and mind-body support, adjusted as you respond.

TherapyCoachingMind-body care

How it is different

A different approach, side by side.

Traditional antidepressants

Serotonin and related systems

IV ketamine therapy at Modern Wellness

Glutamate system and NMDA receptors

A different pathway, linked to neuroplasticity: the brain’s ability to form new connections.

Traditional antidepressants

A daily pill at home

IV ketamine therapy at Modern Wellness

A supervised IV infusion in our clinic

Each infusion happens in a calm, private clinical setting on Michigan Avenue.

Traditional antidepressants

Periodic check-ins

IV ketamine therapy at Modern Wellness

Medical monitoring during each infusion

Our team stays with you from the first minute to the last.

Traditional antidepressants

Often one medication at a time

IV ketamine therapy at Modern Wellness

One part of a broader mental wellness plan

IV ketamine is paired with therapy, coaching and mind-body care, adjusted as you respond.

Our Tree of Life approach

Every symptom has a root. We find yours.

Many treatments focus only on the branches. We look at your whole system, so IV ketamine is supported by strong roots and a clear plan.

The roots

Your foundations: sleep, nutrition, gut health, inflammation and nutrient status.

The trunk

Your brain chemistry: serotonin, dopamine, GABA and how your body handles stress.

The branches

Your treatments: therapy, lifestyle changes, and IV ketamine or other medication when needed.

Your care team

A medical director, a licensed psychiatrist, nurses, therapists and health coaches, working together.

Care around your sessions

One branch of a whole plan.

What happens between sessions matters as much as the session itself. Choose an area to see how we support you.

Therapy & integration

Our licensed therapists help you make sense of what comes up and turn new insight into lasting change.

Often paired with
PsychotherapyIntegration sessionsMindfulness

Testing your roots

Lab testing can show what may be working against your mood, from nutrient levels to inflammation and hormones.

Often paired with
Biomarker testingNutrient statusInflammation

Nutrition & lifestyle

Food, movement and daily habits shape your brain health. Our coaches help you build them, step by step.

Often paired with
Health coachingNutritionMovement

Sleep & stress

Rest and a calmer nervous system give your brain space to recover and form new patterns.

Often paired with
Sleep supportStress careBreathwork

Nourishing your body

IV nutrients and supplements may support energy and recovery, chosen for your body and your labs.

Often paired with
IV therapySupplementsFollow-up labs

Your journey, by design

Four steps, guided with care.

Step 1

Comprehensive evaluation

Your health history, symptoms, current medications, prior treatments and goals.

Step 2

Personalized plan

IV ketamine or Spravato®, the number of sessions and the support around them.

Step 3

Supervised sessions

A calm, private room, with our team monitoring you throughout.

Step 4

Integration & follow-up

Therapy, check-ins and next steps, based on how you respond.

Is it right for you?

An honest first conversation.

It may be a fit if

  • You live with depression and other treatments have not helped enough
  • A provider has diagnosed you with anxiety or PTSD and you want to explore options
  • You want care that is medically supervised and private
  • You are ready to pair sessions with therapy and lifestyle support
  • You want a plan that looks at your whole health

We may wait or suggest another path if

  • You are pregnant or breastfeeding
  • You have uncontrolled high blood pressure or certain heart or blood vessel conditions
  • You have a history of psychosis, or current mania
  • You are actively using alcohol or drugs in a way that affects your health
  • You are in crisis right now. Please call or text 988, or call 911

Your provider confirms what is right for you at your consultation.

What to expect

Before, during and after.

Full pre & post care instructions

Before

  • A full medical and mental health evaluation
  • Follow our eating and drinking instructions for the day
  • Plan a ride home. You should not drive until the next day

During

  • A private, calm room, with music or quiet as you prefer
  • You stay awake. You may feel relaxed, or notice a shift in perception or sense of time
  • Our team checks your vital signs and stays close

After

  • Rest for the remainder of the day
  • Integration with your therapist or coach
  • Follow-ups to adjust your plan as you respond

Questions

IV ketamine therapy, answered.

Prefer a personal conversation? Our concierge team is here to guide you, privately and at your pace. Call (312) 300-0435.

IV ketamine therapy uses carefully dosed IV ketamine, under medical supervision, as one part of a mental wellness plan. It works on the brain’s glutamate system, a different pathway from most antidepressants.

IV ketamine is given through a slow infusion, with the dose set by our medical team. Spravato® is esketamine, a form of ketamine, taken as a nasal spray in our clinic with at least two hours of monitoring. Your provider helps you decide which is right for you.

Spravato® is FDA-approved for certain adults with depression. Ketamine is FDA-approved as an anesthetic, and its use for mental health is off-label. Your provider explains what this means for you at your evaluation.

You stay awake in a calm, supervised setting. Effects vary and may include relaxation, a shift in perception or sense of time, or a temporary feeling of detachment. These effects usually fade within a short time after the session.

Every session is medically supervised, and we check your vital signs throughout. Common short-term effects include nausea, dizziness, raised blood pressure and feeling detached. We review your health history first to make sure IV ketamine is right for you.

Ketamine can be misused outside a medical setting. In our clinic, doses are measured, given only during supervised sessions and never sent home. We screen for substance use before starting.

Your initial cycle is 6 sessions, twice a week, over about three weeks. After that, your provider sets your follow-up and maintenance plan with you.

No. IV ketamine does not replace your current care. Never stop or change a medication without talking to your provider. We are happy to work with your existing care team.

No. Please plan a ride home, and do not drive until the next day after a restful night of sleep.

Yes. IV ketamine can be used as a session inside our Balance and Longevity memberships. Spravato® is not included in memberships and is offered separately. Our team can help you choose the right fit.

Yes. We offer flexible payment plans through CareCredit, Klarna, Affirm, Afterpay and Cherry, so you can split the cost of your care over time. We also accept HSA and FSA cards. Our concierge team is happy to help you choose the option that works best for you.

980 N Michigan Ave, Suite 1379, on the Magnificent Mile in Chicago’s Gold Coast. We’re open Monday to Friday, 9 am to 7 pm.

“IV ketamine therapy opens a quiet doorway, a space where clarity, compassion and self‑understanding can begin to grow.”

Book a consultation

IV ketamine therapy is offered only after a medical evaluation and is not right for everyone. IV ketamine for mental health is an off-label use. Results vary and are not guaranteed. If you are in crisis or thinking about harming yourself, call or text 988 (Suicide & Crisis Lifeline) or call 911 right away.